Oral medications include:
Aubagio (teriflunomide) is a once a day medication that decreases inflammation and reduces the risk of worsening disability.
Mavenclad (cladribine) is taken for only 4-5 days four times over 4 years which results in resetting of the immune system.
Fumarates are taken twice a day to prevent relapses, worsening disability and new MRI activity. Treatments include Tecfidera (dimethyl fumarate), Vumerity (diroximel fumarate) and Bafiertam (monomethyl fumarate).
S1P (sphingosine-1-phosphate receptor modulator) medications are taken once a day to prevent relapses and worsening disability. This class includes Gilenya (fingolimod), Mayzent (siponimod), Ponvory (ponesimod) and Zeposia (ozanimod). Mayzent was shown to be effective in secondary-progressive disease.